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Updated: Jan 13, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity

Published on: January 7, 2019

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LZTR1通过NF-κB1调节上皮MHC-I表达,以调节CD8+ T细胞激活

Rundong Jiang1,2,3, Zhiqin Fang1,2, Yutong Wang1,2,4

  • 1Department of Dermatology, Hunan Engineering Research Center of Skin Health and Disease, Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Cell discovery
|October 30, 2025
PubMed
概括

氨酸拉链状转录调节器1 (LZTR1) 控制表皮组织中CD8+ T细胞的激活. LZTR1通过调节主要组织相容性复合物I类 (MHC-I) 表达来调节炎症,影响自身免疫性疾病.

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