不孕症风险和饮食炎症指数,伊朗的一项病例控制研究
Roya KabodMehri1, Farhad Vahid2, Sheyda Nami3
1Reproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Archives of gynecology and obstetrics
|October 30, 2025
概括
通过饮食炎症指数 (DII) 衡量的促炎症饮食与女性不孕症风险更高有关. 这表明饮食模式可能会影响怀孕.
科学领域:
- 生殖健康 生殖健康
- 营养科学 营养科学
- 流行病学 流行病学
背景情况:
- 不孕症影响全球15%的夫妇,定义为12个月不保护性交后无法怀孕.
- 饮食显著影响炎症因素,可能会影响卵巢储备和生育能力.
- 饮食炎症指数 (DII) 量化了饮食的炎症潜力.
研究的目的:
- 调查饮食炎症指数 (DII) 与不孕症之间的关联.
- 评估促炎症饮食是否会增加不孕症的风险.
主要方法:
- 一项涉及123名不育妇女和123名健康对照者的病例控制研究.
- 使用经过验证的食物频率问卷 (FFQ) 评估的食物摄入量.
- 饮食炎症指数 (DII) 计算和逻辑回归用于分析与不孕症和卵巢储备的关系.
主要成果:
- 较高的DII得分与不孕症风险增加显著相关 (OR=2.08,95% CI=1.024-4.248,P=0.043).
- 这一关联在调整多个混因素 (包括年龄,BMI,生活方式和潜在的健康状况) 之后仍然显著.
- 对不孕症特定因素的进一步调整并没有改变观察到的关系.
结论:
- 饮食炎症指数 (DII) 显示了与不孕症的积极关联.
- 具有较高炎症潜力的饮食可能会增加患不孕症的可能性.
- 需要进一步的研究来阐明连接炎症饮食和不孕不育的机制.
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