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Updated: Jan 13, 2026

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DNGR-1信号限制了树突细胞激活,以实现最佳的抗原交叉呈现

Michael D Buck1, Tomás Castro-Dopico2, Oliver Schulz2

  • 1Immunobiology Laboratory, The Francis Crick Institute, London, UK. michael.buck@crick.ac.uk.

The EMBO journal
|October 30, 2025
PubMed
概括

树突细胞 (DCs) 中的DNGR-1受体信号优先考虑抗原交叉呈现而不是细胞激活. 这种平衡可以尽量减少死细胞的炎症,影响对癌症和病毒的免疫反应.

关键词:
激活活动 激活活动这就是CLEC9A.交叉呈现交叉呈现在DNGR-1中,它是DNGR-1.cDC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC1DC2DC1DC1DC1DC2DC2DC2DC2DC2DC3DC4DC3DC4DC4DC5

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