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Updated: Jan 13, 2026

Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution
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Imaging Cleared Embryonic and Postnatal Hearts at Single-cell Resolution

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发育中的人类心脏的时空空间基因表达和细胞动态

Enikő Lázár1,2, Raphaël Mauron3, Žaneta Andrusivová3

  • 1Department of Gene Technology, KTH Royal Institute of Technology, Science for Life Laboratory, Solna, Sweden. eniko.lazar@scilifelab.se.

Nature genetics
|October 30, 2025
PubMed
概括

这项研究绘制了人类心脏发育中的分子和细胞格局. 它揭示了关于心脏发育,心脏结构以及与先天性心脏病的潜在联系的新细节.

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相关概念视频

Development of the Heart01:27

Development of the Heart

The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
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