在液体活检时代,超越组织:病理学家的观点和见解
Mario Urso1, Davide Seminati2, Daniela Pilla2
1Department of Medicine and Surgery, Pathology, University of Milano-Bicocca, Monza, Italy.
概括
液体活检提供了最少侵入性的癌症分子分析. 细胞病理学将这些测试从各种体液中整合在一起,通过人工智能支持更好的解释来解决挑战.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 生物技术是生物技术.
背景情况:
- 液体活检可以使用血进行微创性癌症分子分析.
- 细胞学样本,如脏液,脑脊液和尿液,也是分子测试的宝贵来源.
研究的目的:
- 审查细胞病理学在将液体活检整合到临床实践中的作用.
- 讨论与不同类型的液体活检样本相关的预分析和分析挑战.
- 探索人工智能在提高液体活检样本的形态和分子解释方面的潜力.
主要方法:
- 关于液体活检和细胞病理学的当前文献的叙事综述.
- 讨论各种细胞学样本的预分析和分析考虑.
- 探索人工智能在细胞病理学中的应用,用于液体活检分析.
主要成果:
- 细胞病理学在液体活检的临床整合中起着至关重要的作用.
- 各种细胞学标本存在独特的预分析和分析挑战.
- 人工智能在改善液体活检的形态和分子数据的解释方面表现有前途.
结论:
- 细胞病理学对于成功实施癌症诊断中的液体活检至关重要.
- 解决样本特定的挑战是最大限度地提高液体活检效益的关键.
- 人工智能可以显著提高液体活检分析的准确性和效率.
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