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Updated: Jan 12, 2026

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
10:44

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs

Published on: May 15, 2019

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多发性骨髓瘤的梅齐多米德:关注第二阶段试验数据.

Clifton C Mo1, Yuxin Liu1, Omar Nadeem1

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Jerome Lipper Center for Multiple Myeloma Research, Harvard Medical School, Boston, MA, USA.

Expert opinion on emerging drugs
|October 30, 2025
PubMed
概括

梅西格多米德是一种新的cereblon E3酶调节剂,在复发性/耐药性多发性髓瘤 (MM) 的早期试验中显示出有前途的临床疗效. 它显示出卓越的功效和协同效应,为难以治疗的MM患者提供了新的希望.

关键词:
这是CELMoD.这就是为什么Cereblon.免疫调节器是一种免疫调节器.梅西格多米德的使用方法多发性骨髓瘤是多发性骨髓瘤的一种.阶段1/2阶段1/2阶段耐火材料 耐火材料 耐火材料这是一个复发的复发.

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