从青春期到青春期的骨矿物质积累和峰值骨质量:一个纵向队列研究
Arzhang Naseri1, Farnaz Atighi1, Alireza Keshtkar2
1Endocrinology and Metabolism Research Center Shiraz University of Medical Sciences Shiraz Iran.
Health science reports
|October 30, 2025
概括
峰值骨质量通常在30多岁中期达到,男性的骨矿物质含量和密度比女性高. 年龄,BMI,性别,SES和运动等因素会影响骨在生长过程中的积累.
科学领域:
- 整形外科和体育医学
- 儿科 儿科 儿科
- 公共卫生 公共卫生
背景情况:
- 了解骨质积累对于预防骨质疏松症至关重要.
- 骨矿物质含量 (BMC),骨矿物质密度 (BMD) 和骨矿物质表面密度 (BMAD) 的纵向变化是成长期间骨健康的关键指标.
- 影响骨质量的因素包括青春期,年龄,体重指数 (BMI),性别,社会经济地位 (SES) 和习惯性炼.
研究的目的:
- 为了研究生长过程中的BMC,BMD和BMAD的纵向变化.
- 为了估计男性和女性达到峰值骨质量 (PBM) 的年龄.
- 检查各种因素对青春期和成年早期骨参数的影响.
主要方法:
- 对159名参与者的回顾性队列研究.
- 双能X射线吸收计 (DXA) 用于骨密度计.
- 通过医生管理的问卷收集人体统计,人口统计,青春期,病史,SES和运动数据.
主要成果:
- 随着年龄和青春期阶段的增长,全身 BMC (TBBMC) 和 BMD (TBBMD) 的变化率下降.
- 男性的TBBMC和TBBMD变化率高于女性,直到18岁.
- 峰值TBBMC和TBBMD是在二十多岁中期达到的,女性比男性更早达到PBM. 年龄较大,BMI较高,男性性别较高,SES较高和体育活动对TBBMC和TBBMD产生了积极的影响.
结论:
- 骨积累在青春期比成年早期更为显著.
- 峰值骨质量通常在第三个十年中期达到,女性更早达到.
- 年龄,性别,BMI,SES和运动是青春期和早期成年期骨矿物质含量和密度的积极影响者.
关键词:
青春期 青春期 青春期骨矿物质表面密度 表面密度骨矿物质含量 骨矿物质含量骨矿物质密度 骨矿物质密度增长的增长增长的增长增长的增长.峰值骨质量峰值 骨质量峰值 骨质量峰值青春期的青春期,就是青春期.年轻人的成年期.更多相关视频
06:59Author Spotlight: An Economic and Efficient Method for Quantitative Evaluation of Bone Microarchitecture in a Murine Osteoporosis Model
Published on: September 8, 2023
3.4K
07:12Semiautomated Longitudinal Microcomputed Tomography-based Quantitative Structural Analysis of a Nude Rat Osteoporosis-related Vertebral Fracture Model
Published on: September 28, 2017
8.6K
相关概念视频
01:29Bone Disorders
5.0K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
5.0K
01:09Changes in the Appendicular Skeleton with Age
3.3K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.3K
01:40Bone Remodeling
40.2K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
40.2K
01:29Bone Formation by Intramembranous Ossification
10.1K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
10.1K
01:17Hormones and Bone Tissue
3.7K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.7K
01:24Bone Formation by Endochondral Ossification
8.3K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
8.3K