不同内药物的有效性在治疗上性牙周炎
Kamil Shahnawaz1, Priyanka Sarangi2, Sukanta Kumar Satapathy3
1Head of Department, Department of Dentistry, Darbhanga Medical College, Laheriasarai, Bihar, India.
Journal of pharmacy & bioallied sciences
|October 30, 2025
概括
三重抗生素糊在根通道中有效地消除了Enterococcus faecalis,在对顶牙周炎治疗的研究中,其表现优于氧化和氧化凝.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 微生物学 微生物学
- 牙科材料科学 牙科材料科学
背景情况:
- 牙周炎源于脉感染,需要彻底的根管消毒才能成功进行内牙治疗.
- 细菌污染和宿主反应是牙周炎病原发生的关键因素.
研究的目的:
- 评估不同内药物的抗微生物疗效,以对抗Enterococcus faecalis,在一个试验室模型的顶端牙周炎.
- 为了比较三重抗生素糊 (TAP),氧化和2%的氧化 (CHX) 凝在减少根运河系统内的微生物负载方面的有效性.
主要方法:
- 带有诱导的顶端牙周炎的单根人类牙被仪器检查并感染了Enterococcus faecalis.
- 牙被分为四组:盐水 (对照组),氧化,三重抗生素糊和2%的氧化凝.
- 药物被放置在根通道7天,和微生物样本收集治疗前和治疗后量化殖民地形成单位 (CFU).
主要成果:
- 与对照组相比,所有测试药物都显著降低了CFU (P <0.05).
- 三重抗生素糊表现出最高的抗菌疗效,其次是赫西丁凝和氧化.
- 与其他治疗方法相比,TAP显示出明显优异的结果 (P < 0.01).
结论:
- 三重抗生素糊是一种高效的内运河药物,用于消除内牙治疗中的Enterococcus faecalis.
- 塔普对E. faecalis表现出强大的抗菌活性,使其成为治疗顶端牙周炎的有希望的选择.
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