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Updated: Jan 12, 2026

Frailty Assessment in an Aging Mouse Model
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吸烟与嗅觉功能在脆弱性上的相互作用:基于人口的横截面研究.

Guangyao Li1, Fangzhou Ye2, Keguang Chen1

  • 1Department of Otorhinolaryngology - Head and Neck Surgery Shanghai Zhongshan Hospital Affiliated to Fudan University Shanghai PR China.

Health science reports
|October 30, 2025
PubMed
概括

吸烟和嗅觉功能障碍协同增加老年人的脆弱风险. 早期查感官变化和戒烟对于预防虚弱至关重要.

关键词:
尼汉斯 (NHANES) 是一个名人.脆弱 脆弱 脆弱 脆弱 脆弱嗅觉障碍是一种嗅觉障碍.吸烟是为了吸烟.

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科学领域:

  • 老年学是指老年学的学科.
  • 公共卫生 公共卫生
  • 流行病学 流行病学

背景情况:

  • 虚弱是关键的衰老综合征,与不良结果有关.
  • 吸烟和嗅觉功能障碍是众所周知的脆弱性风险因素.
  • 吸烟和虚弱的嗅觉功能障碍之间的相互作用还没有得到充分研究.

研究的目的:

  • 调查吸烟和嗅觉功能与脆弱性的独立和联合关联.
  • 检查吸烟和嗅觉功能障碍对脆弱风险的潜在协同效应.

主要方法:

  • 利用了来自5192名参与者的国家健康和营养检查调查 (NHANES) 数据 (2011-2014).
  • 通过问卷评估吸烟状态和自我报告的嗅觉功能.
  • 使用36项脆弱指数 (FI>0.2) 定义脆弱性,并使用后勤回归进行分析.

主要成果:

  • 当前吸烟和嗅觉功能的改变都与较高的脆弱性风险独立相关.
  • 在吸烟和嗅觉功能之间发现了显著的相互作用 (P=0.001).
  • 嗅觉功能改变的吸烟者表现出最高的脆弱率 (OR=2.49,95% CI:1.88-3.31).

结论:

  • 吸烟,嗅觉功能障碍和虚弱之间存在协同关系.
  • 强调感官查和行为评估对老年人,特别是吸烟者的重要性.
  • 为早期脆弱性识别和预防提供医疗保健策略的信息.