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Updated: Jan 12, 2026

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
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一种新的N6-甲基氨酸抑制剂,塞拉斯特罗,通过向IGF2BP3缓解类风湿性关节炎

Qishun Geng1,2, Yi Jiao3,4, Wenya Diao3,4

  • 1Department of Pharmacy The First Affiliated Hospital of Zhengzhou University Zhengzhou Henan China.

MedComm
|October 30, 2025
PubMed
概括

塞拉斯 (CEL) 向胰岛素样生长因子-2 mRNA结合蛋白-3 (IGF2BP3),以抑制类风湿性关节炎 (RA) 的进展. 这种药物通过影响IGF2BP3/RASGRF1/mTORC1通路来减少纤维细胞样同胞细胞增殖和巨细胞炎症.

关键词:
在 IGF2BP3BP3 中.塞拉斯特罗尔 (celastrol) 是一种细胞的增殖细胞的增殖.炎症激活的炎症激活类风湿性关节炎 类风湿性关节炎

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