全球白风专家和患者的合作倡议,以定义白风活动 (ACTIVE):研究协议
Liesbeth Delbaere1,2, Lise Vanden Broucke1,2, Albert Wolkerstorfer3
1Department of Dermatology, Ghent University Hospital, Ghent, Belgium.
The Journal of dermatological treatment
|October 30, 2025
概括
全球白风专家和患者合作倡议 (ACTIVE) 项目标准化了白风活动定义. 这种基于共识的方法提高了疾病评估的一致性和临床试验可靠性.
科学领域:
- 皮肤病学 皮肤病学
- 自免疫性疾病 自免疫性疾病
- 临床研究 临床研究
背景情况:
- Vitiligo 活动评估缺乏标准化的标准.
- 不一致的定义阻碍了疾病管理和临床试验的可比性.
研究的目的:
- 制定标准化的定义和标准来评估白风病的活性.
- 建立基于共识的,多利益相关方的方法来评估白风活动.
主要方法:
- 文献评论和代的e-Delphi调查.
- 包括国际白风专家和患者在内的共识会议.
- 将疾病活动分为渐进型和稳定的类别进行分类.
主要成果:
- 在多个中心的疾病活动定义中提高一致性.
- 改善了白风研究结果的可比性.
- 更可靠的临床试验患者纳入标准.
结论:
- 该ACTIVE项目为标准化白风活动评估提供了一个框架.
- 这一举措将促进更好的疾病管理和促进治疗研究.
- 关于白风活动定义的全球共识对于推进患者护理至关重要.
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