睡眠障碍与绝经后妇女的认知障碍有关
Álvaro Monterrosa-Castro1, Peter Chedraui2, Juan E Blümel2,3
1Grupo de Investigación Salud de la Mujer, Universidad de Cartagena, Cartagena, Colombia.
Women & health
|October 30, 2025
概括
严重的睡眠问题与绝经后妇女的轻度认知障碍 (MCI) 有关. 这种关联在多个国家观察到,突出显示了睡眠质量.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 妇女健康 妇女健康
背景情况:
- 轻度认知障碍 (MCI) 影响老年人群的认知功能.
- 绝经后的女性代表了一个易受睡眠障碍和认知变化的人群.
- 了解与MCI相关的因素对于开发有针对性的干预措施至关重要.
研究的目的:
- 调查绝经后妇女严重睡眠问题和轻度认知障碍 (MCI) 之间的关联.
- 确定其他影响MCI风险的因素,在这个人群中.
主要方法:
- 这是一项涉及9个拉丁美洲国家的1,185名绝经后妇女 (70岁以下) 的跨界,跨国研究.
- 使用蒙特利尔认知评估 (MoCA) 评估的轻度认知障碍 (MCI).
- 使用更年期评分表 (MRS) 和詹金斯睡眠表 (JSS) 评估的严重睡眠问题.
- 调整后勤回归模型分析了睡眠问题与MCI之间的关联,控制共变量.
主要成果:
- 严重的睡眠问题在患有MCI的妇女中明显更为普遍,与没有MCI的妇女相比,无论使用的睡眠评估工具 (MRS和JSS,p < .001).
- 调整后的模型显示,严重的睡眠问题独立地与更高的MCI概率相关 (MRS的aOR=1.81,JSS的aOR=1.88).
- 身体不活动和更高的平价增加了MCI的可能性,而更年期荷尔蒙疗法使用和高等教育与降低MCI风险有关.
结论:
- 严重的睡眠问题独立地与更年期后拉丁美洲女性轻度认知障碍的可能性增加有关.
- 包括身体不活动,性别平等,更年期荷尔蒙疗法使用和教育程度在内的因素也在MCI中发挥着重要作用.
- 解决睡眠障碍可能是缓解绝经后妇女认知衰退的潜在策略.
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