在辅助生殖技术中研究性质细胞捐赠的结果:一项回顾性研究
Sofia Soares1, Carla Leal1,2,3, Márcia Barreiro1,2,3
1ICBAS - School of Medicine and Biomedical Sciences, UMIB - Unit for Multidisciplinary Research in Biomedicine, University of Porto, Porto, Portugal.
JBRA assisted reproduction
|October 30, 2025
概括
使用配子捐赠的辅助生殖技术 (ART) 导致高早产率和低出生体重,特别是多胎妊娠. 建议进行单个胚胎移植,以改善ART周期中的产科和新生儿结局.
科学领域:
- 生殖医学 生殖医学
- 产科 产科 产科 产科 产科
- 新生儿科学 新生儿科学
背景情况:
- 辅助生殖技术 (ART) 在治疗不孕症方面发挥着至关重要的作用.
- 雌激素捐赠是ART的关键组成部分,为面对雌激素相关挑战的个人和夫妇实现受孕.
- 评估性质细胞捐赠周期的结果对于优化患者护理和成功率至关重要.
研究的目的:
- 评估和描述利用性质细胞捐赠的辅助生殖技术 (ART) 周期.
- 分析因性子捐献导致的怀孕中相关的产科和新生儿结局.
- 确定影响ART周期成功和相关风险的因素.
主要方法:
- 从2011年到2021年,对238个性质细胞捐赠周期进行了回顾性分析.
- 收集包括接受者人口统计,不孕因素,ART技术和怀孕结果在内的变量.
- 使用IBM SPSS统计27进行统计分析 (p<0.05显著性).
主要成果:
- 精子捐赠:29.4%的早产,24.3%的没有持续的怀孕,47.7%的剖腹产.
- 在29.3%的单生子和69%的双胞胎中观察到低出生体重.
- 卵子捐赠:40%的早产,43.4%的低出生体重;多胎妊娠增加了风险.
结论:
- 在性子捐赠ART周期中多胎妊娠的高发病率.
- 建议单个胚胎移植,特别是对于较老的卵子接受者.
- 强调患者的风险/益处教育和全面的孕产妇/胎儿监测.
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