很愿意使用和推多西环林的暴露后预防,以预防秘鲁的细菌性性传播疾病
Jorge A Gallardo-Cartagena1, Dora L G German-Quiñones1, Fanny G Rosas-Benancio1
1Centro de Investigaciones Tecnológicas, Biomédicas y Medioambientales, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Sexually transmitted diseases
|October 30, 2025
概括
在秘鲁,与男性发生性关系的男性和跨性别女性中发现了使用多西环林暴露后预防 (doxy-PEP) 的高意愿. 医疗保健提供者也表现出强烈的意愿,推doxy-PEP,支持其融入性健康服务.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 性健康 性的健康
背景情况:
- 细菌性传播感染 (STD) 是秘鲁与男性发生性关系的男性 (MSM) 和跨性别女性 (TGW) 的重要关注点.
- 多西环素暴露后预防 (doxy-PEP) 是一种潜在的预防策略,但拉丁美洲的数据很少.
研究的目的:
- 评估MSM和TGW在秘鲁利马使用doxy-PEP的意愿.
- 评估医疗保健提供者 (HCP) 愿意推doxy-PEP的意愿.
- 确定与使用doxy-PEP的意愿相关的因素.
主要方法:
- 在2024年9月至10月期间,两项在线调查在秘鲁利马进行.
- 一项调查针对MSM和TGW关于doxy-PEP使用.
- 第二次调查的重点是医疗保健工作者推doxy-PEP的意愿,后勤回归用于分析意愿的相关性.
主要成果:
- 82.1%的MSM和TGW表示愿意使用doxy-PEP,其中34.2%表示很愿意. 与高意愿相关的因素包括更多的性伴侣数量,先前的HIV暴露前预防 (HIV-PrEP) 使用,以及与艾滋病毒感染.
- 参与者更喜欢多西-PEP而不是每日多西环素 (64.0%vs28.6%).
- 在参与HIV/STI护理的医疗保健工作者中,87.1%的人愿意推doxy-PEP,特别是如果它被列入国家指南. 担忧包括诊断能力和非官方使用.
结论:
- 在秘鲁的客户和医疗人员中观察到大量使用和推doxy-PEP的意愿.
- 这些发现支持将doxy-PEP纳入拉丁美洲的性健康服务.
- 进一步的研究应解决医疗专家对诊断能力和非官方使用的担忧.
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