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Updated: Jan 6, 2026

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues

Published on: July 14, 2015

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由人工智能驱动的框架,用于从整个蛋白质宇宙中发现合成结合蛋白质类支架

Zixin Duan1, Yafeng Liang1, Jing Zhang1

  • 1School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing 401331, China.

Briefings in bioinformatics
|October 30, 2025
PubMed
概括

这项研究引入了一个AI框架,从蛋白质组中发现新的合成结合蛋白 (SBP) 类支架. 人工智能方法识别结构相似的蛋白质,即使是低序列标识,有助于蛋白质结合剂设计.

关键词:
人工智能的人工智能是人工智能.工程化蛋白质支架的工程化蛋白质支架.蛋白质设计 蛋白质设计蛋白质的进化 蛋白质的进化合成结合蛋白质的结合蛋白质.

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