疼痛反应对睡眠恶化和健康结果之间的关联
Christina X Mu1, Brent J Small2, Christina S McCrae3
1Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, United States.
概括
对于睡眠不足的疼痛反应性较高的个体经历了更多的痛苦. 这种疼痛反应性没有预测随着时间的推移,痛苦或慢性疾病的变化.
科学领域:
- 睡眠科学 睡眠科学
- 疼痛研究 疼痛研究
- 心理上的痛苦 心理上的痛苦
背景情况:
- 睡眠障碍和疼痛在成年人中很常见.
- 对睡眠恶化的疼痛反应意味着与睡眠持续时间或质量相关的疼痛水平的个体变化.
研究的目的:
- 调查与睡眠相关的疼痛反应,心理困扰和慢性疾病的数量之间的截面和纵向关联.
- 了解个人对睡眠变化的疼痛反应的差异如何与心理健康和健康状况有关.
主要方法:
- 利用工作,家庭和健康研究 (n=311) 的数据,在八天内每天记录日记.
- 采用多层结构方程模型和增长曲线模型,控制社会人口统计和健康共变量.
- 进行了敏感性分析,对睡眠和疼痛药物进行调整,并按年龄分层分析.
主要成果:
- 较高的疼痛强度对睡眠时间缩短和睡眠质量差的反应性与同时增加的心理痛苦相关.
- 对睡眠状况恶化的疼痛反应与随着时间的推移而发生的痛苦变化或慢性疾病的数量没有显著相关.
- 与假设相反,较高的疼痛位置对较差睡眠质量的反应性与长度上减少的痛苦和较少的慢性疾病有关.
结论:
- 对睡眠不足的疼痛反应性升高与更大的当前心理痛苦有关.
- 对睡眠状况恶化的疼痛反应不能预测未来的痛苦或这种队列中慢性疾病的发展.
- 建议在更大,多样化的群体中进行进一步的研究,并进行延长的随访,以探索这些关系.
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