从性结肠炎到粉样风:一个基于案例的审查
Sultan Özkurt1, Döndü Üsküdar Cansu2, Uygar Yildirim1
1Division of Nephrology, Department of Internal Medicine, Eskişehir Osmangazi University, Eskişehir, Turkey.
Rheumatology international
|October 30, 2025
概括
粉样菌风暴是一种罕见的,急性损伤并发症AA粉样菌症,通常由感染引发. 这一案例突出了性结肠炎作为一个原因,脏病末期和死亡率很高.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 家庭地中海热 (FMF) 的并发症包括AA粉样化症和粉样性脏病.
- 粉样菌风暴是AA粉样菌症的急性表现,伴有快速功能衰竭.
- 它很少被报告,通常与FMF相关,但可以是AA氨基粉症的初始表现.
研究的目的:
- 报告第一个与性结肠炎相关的粉样风暴病例.
- 审查有关粉样风的文献,包括原因,临床特征和结果.
- 为了强调这种罕见但严重的疾病.
主要方法:
- 一个患有性结肠炎和粉样风的患者的病例介绍.
- 36名患有粉样风的患者的文献综述.
- 分析原因,触发因素,末期病 (ESRD) 率和死亡率.
主要成果:
- 报告的粉样性风暴病例与性结肠炎有关,呈现急性损伤和高蛋白尿.
- 文献综述确定FMF是最常见的原因 (5.5%),但还注意到了性结肠炎,性脊柱炎和自身炎症性疾病等其他疾病.
- 感染是最常见的触发因素;ESRD率达到67%,死亡率在33%至67%之间.
结论:
- 粉样菌风暴是AA粉样菌症的严重,急性并发症,具有显著的发病率和死亡率.
- 性结肠炎被确定为潜在的潜在原因.
- 及时识别和管理,包括支持性护理和IL-1封锁,至关重要,尽管结果仍然很差.
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