相关实验视频

Updated: Jan 12, 2026

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies

Published on: March 12, 2014

非小细胞肺癌 (NSCLC) 的外科免疫疗法

Sarafina Urenna Otis¹, Giuseppe Luigi Banna^2,3, Akash Maniam⁴

¹Medical Sciences Division, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, England.

Current oncology reports

|October 30, 2025

概括

术后免疫疗法,包括免疫检查点抑制剂 (ICI),现在用于早期非小细胞肺癌 (NSCLC). 研究正在进行中,以优化治疗方案,并探索新型组合,如抗体药物联合体 (ADCs).

科学领域:

在瘤学瘤学.
免疫治疗是一种免疫疗法.
胸部外科手术胸部外科手术

背景情况:

免疫疗法已经从晚期癌症扩展到早期癌症.
免疫检查点抑制剂 (ICI) 现在广泛应用于可切除的早期非小细胞肺癌 (NSCLC).

研究的目的:

审查早期NSCLC的术后免疫疗法.
突出最近的发展,剩下的问题和未来的前景.

主要方法:

关于NSCLC外科手术期免疫疗法的最新进展的文献综述.
对当前临床试验数据和监管批准的分析.

主要成果:

在可切除早期NSCLC (IB-IIIA) 中,ICI已被批准用于术后使用.
有关ICI与向治疗的结合存在担忧,原因是毒性和疗效.
抗体药物合物 (ADC) 是有前途的,试验调查了它们与肺癌免疫治疗的结合.

结论:

经手术期免疫疗法对早期NSCLC具有显著的前景.
需要进一步的研究来优化治疗方案和组合策略.
术后免疫治疗的全部潜力需要通过持续的研究进一步实现.

关键词:

抗体药物联合体的抗体药物联合体在早期阶段.免疫检查点抑制剂免疫检查点抑制剂免疫治疗是一种免疫疗法.在NSCLCLC中,我们可以看到.经期操作性经期操作性

更多相关视频

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

Published on: February 12, 2017

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Orthotopic Transplantation of Syngeneic Lung Adenocarcinoma Cells to Study PD-L1 Expression

Published on: January 19, 2019

相关概念视频

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...