静脉偏头痛的预防性管理:系统性审查
Hussain Ali Almohammed1, Husna Irfan Thalib2, Kawthar Faisal Kushara3
1College of Medicine, King Faisal University, Al Ahsa, Saudi Arabia.
Annals of clinical and translational neurology
|October 30, 2025
概括
普罗普拉诺洛尔和托皮拉对前庭偏头痛 (VM) 预防有希望. 新兴的抗CGRP疗法可能有助于困难的病例,但需要更多的研究来标准化治疗.
科学领域:
- 神经学 神经学
- 眼科医生 眼科 眼科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 静脉偏头痛 (VM) 是一种常见的神经疾病,会引起偶发性和显著的功能障碍.
- 目前对VM的预防性治疗选择缺乏共识.
- 本审查评估了VM管理的干预措施.
研究的目的:
- 系统地审查前体偏头痛 (VM) 的药理和非药理干预措施的疗效和安全性.
主要方法:
- 按照PRISMA 2020指南进行系统审查.
- 搜索了PubMed,科学网和谷歌学者直到2025年4月.
- 包括对成人预防性VM治疗的RCT和队列研究,评估偏差风险.
主要成果:
- 包括9项研究 (n=687).
- 普罗普拉诺洛尔和托皮拉美特有效地减少了VM症状.
- 抗CGRP单克隆抗体显示出良好的疗效和耐受性.
- 垂体康复显示了作为辅助治疗的功能益处.
结论:
- 适度的证据支持propranolol和topiramate作为第一线VM预防.
- 抗CGRP剂显示出耐火VM的潜力.
- 为了标准化治疗方案,还需要进一步的大规模试验.
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