[在McKeown食道切除术后宫解剖失败的预测]
E A Toneev1,2, O V Pikin3, R F Shagdaleev2
1Regional Clinical Oncology Dispensary, Ulyanovsk, Russia.
Khirurgiia
|October 30, 2025
概括
血小板-淋巴细胞比率,预后营养指数和全身免疫炎症指数预测麦克凯恩食道切除术后宫解剖失败. 为了风险预测,开发了一个名图.
科学领域:
- 手术瘤学手术瘤学
- 胃肠道手术 胃肠道手术
- 预测建模预测建模
背景情况:
- 宫解剖缺陷是McKeown食道切除术后的严重并发症,因为食道癌.
- 确定可靠的风险因素对于改善患者的治疗结果和外科手术策略至关重要.
研究的目的:
- 确定McKeown食道切除术后宫解剖失败的独立风险因素.
- 开发和验证一个预测性模型,用于解断的失败.
主要方法:
- 对69例McKeown食道切除术中部胸腔食道癌的回顾性分析 (2019-2023年).
- 后勤回归分析以确定重要的预测因素.
- 使用人工智能和机器学习开发名ogram.
主要成果:
- 解断失败的发生率为18.8%.
- 血小板-淋巴细胞比率 (PLR),预后营养指数 (PNI) 和全身免疫炎症指数 (SII) 被确定为独立的风险因素.
- 预测模型表现出高准确度 (AUC=0.953),灵敏度为84.6%,特异性为87.5%.
结论:
- 在McKeown食道切除术后,PLR,PNI和SII是宫静脉泄漏的重要预测因素.
- 一个经过验证的诺米图可以有效地预测道泄漏的概率,帮助临床决策.
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