风险人群中无症状mopox的查:一个横截面研究
Inés Armenteros-Yeguas1,2,3,4, Reynaldo Homen2,4,5, Adrián Valls2,4
1Centro Sanitario Sandoval, Hospital Universitario Clínico San Carlos, Madrid, Spain.
PloS one
|October 30, 2025
概括
无症状的mpox (麻疹病毒) 感染很少见,唯一检测到的病例是在采样后出现症状的. 这表明无症状的携带者不太可能导致西班牙目前的mopox疫情.
科学领域:
- 传染性疾病 传染性疾病
- 病毒学 病毒学
- 公共卫生 公共卫生
背景情况:
- 麻疹是一种由麻疹病毒引起的病毒性疾病,在2022年全球病例激增,主要是通过性传播传播.
- 在无症状个体中未被检测到的mopox循环的可能性需要进行调查.
研究的目的:
- 评估在参加性传播感染 (STIs) 诊所的个人中无症状mopox感染的流行率.
- 评估无症状携带者在正在进行的mopox传播动态中的作用.
主要方法:
- 在2023年7月至10月期间,在西班牙马德里进行了一项观察性横截面研究.
- 从343名无症状参与者中采集了喉和直肠拭子,以测试mopox和细菌性传播感染.
- 收集和分析了社会人口,临床和行为数据.
主要成果:
- 发现无症状mopox的患病率为0.3% (1名参与者),后来出现症状.
- 这个单一病例表明,在这个人群中,完全无症状的mopox感染不太可能发生.
- 在21.6%的参与者中检测到其他性传播疾病,突出显示了需要进行常规性传播疾病查的必要性.
结论:
- 无症状的mpox携带者似乎不是西班牙当前mpox流行病的重要因素.
- 常规查无症状的细菌性传染病建议在风险人群.
- 对于无症状个体的Mopox测试策略应该是特定于环境的.
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