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Updated: Jan 12, 2026

Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays
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Assessment of Resistance to Tyrosine Kinase Inhibitors by an Interrogation of Signal Transduction Pathways by Antibody Arrays

Published on: September 19, 2018

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准MERTK氨酸激酶:虚拟查和分子动力学的洞察力,用于抗癌药物开发

Kashif Kifayat1, Kamaljot Singh2, Mahmood Khan3

  • 1Division of Hepatobiliary and Pancreatic Surgery, Department of General Surgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, China.

PloS one
|October 30, 2025
PubMed
概括

这项研究确定了四种新型药物化合物,它们强烈抑制MERTK蛋白,这是各种癌症的关键标. 这些化合物通过稳定MERTK蛋白质结构来开发新的癌症治疗方法.

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