完成MDP和D12的顺序不会影响喘息反应:一项随机对照试验
Isabelle Wemar1, Jacob Sandberg1,2, Max Olsson1
1Department of Clinical Sciences Lund, Respiratory Medicine, Allergology and Palliative Medicine, Lund University Faculty of Medicine, Lund, Sweden.
Chronic respiratory disease
|October 30, 2025
概括
填写多维呼吸障碍概况 (MDP) 和呼吸障碍-12 (D12) 问卷的顺序不会显著影响心肺呼吸系统患者的呼吸困难得分. 这一发现支持在临床实践和研究中灵活的问卷排序.
科学领域:
- 心肺医学 心肺医学
- 临床研究方法论 临床研究方法论
- 患者报告的结果
背景情况:
- 呼吸困难是各种医疗条件中普遍存在和令人痛苦的症状.
- 多维呼吸障碍概况 (MDP) 和呼吸障碍-12 (D12) 评估了呼吸困难的不同维度.
- 了解问卷管理顺序对于可靠的症状评估至关重要.
研究的目的:
- 调查填写MDP和D12问卷的顺序是否会影响喘息反应.
- 确定问卷顺序对心肺呼吸系统疾病患者报告结果的影响.
主要方法:
- 在纵向临床研究中嵌入的随机对照试验.
- 182名心肺呼吸系统疾病的门诊患者被随机分配为先完成MDP或先完成D12.
- 主要结局是D12总得分的平均差异;次要结局包括子域得分,与最小临床重要差异 (MCID) 相比.
主要成果:
- 两组之间的D12总得分平均值没有显著差异 (平均差异-1.5,p=0.26).
- 亚域得分的平均差异也低于各自的MCID.
- 参与者的特征在两个随机组中都是相似的.
结论:
- 填写MDP和D12问卷的顺序没有显著影响喘息得分.
- 该研究表明,在未来的研究和临床环境中,问卷顺序的灵活性.
- 缺乏统计能力限制了检测较小,临床上显著差异的能力.
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