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Updated: Jan 12, 2026

Advances in Human Induced Pluripotent Stem Cell-Derived Chimeric Antigen Receptor-Expressing Natural Killer Cells
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CliCAR:一种非遗传CAR工程策略,以赋予NK细胞针对癌症免疫疗法的能力

Su Yeon Lim1, Yeongbeom Kim1, Seungmin Han2

  • 1Department of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Republic of Korea.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
|October 30, 2025
PubMed
概括

一种基于蛋白质的新疗法,即重组化学抗原受体融合蛋白 (CliCAR),使自然杀手 (NK) 细胞能够在不进行基因编辑的情况下向HER2阳性癌症. 这种非病毒性方法为强效,现成的免疫细胞疗法提供了安全,快速的策略.

关键词:
化学抗原受体 化学抗原受体免疫治疗是一种免疫疗法.在 NK 细胞中, NK 细胞是最重要的.重组聚变蛋白是重组聚变蛋白中的一种.有针对性的交付.

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