相关实验视频

Updated: Jan 12, 2026

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

化学污染物在环境矩阵中的发生,使用非向分析和基于效应的方法:系统的定量文献综述

Mikaela J Radke¹, Sarah L Cresswell², Frederic D L Leusch¹

¹Australian Rivers Institute, School of Environment and Science, Griffith University, 4111, Nathan, Australia.

The Science of the total environment

|October 30, 2025

概括

本次审查强调,沉积物和废水是化学污染物分析的常见环境矩阵. 未知极变产物和新出现的污染物有助于毒性,需要进一步研究.

科学领域:

环境化学环境化学
生态毒理学生态毒理学
分析化学分析化学

背景情况:

非定向分析 (NTA) 与效果导向分析 (EDA) 相结合,对于识别环境污染物至关重要.
之前的审查集中在特定的矩阵或污染物类别上,在了解NTA-EDA在各种环境样本中的应用方面存在差距.

研究的目的:

系统地审查使用NTA-EDA在生态毒性研究中发现的样本矩阵和化学污染物.
为了识别NTA-EDA应用程序中代表性不足的环境矩阵.
评估已识别的化学污染物与观察到的毒性之间的关系.

主要方法:

使用NTA-EDA进行的95项生态毒性研究的定量文献综述.
根据化合物类别 (例如,持久性有机污染物,内分泌干扰化学物质) 和化合物类型 (例如,药品,杀虫剂,可塑剂) 进行识别化学品的分类.
分析所分析的环境矩阵的分析及其在经过审查的文献中的表示.

主要成果:

沉积物和废水废水是最常被分析的矩阵.
持久性有机污染物 (POP) 和内分泌干扰化学物质 (EDC) 是主要的化学品类别.
鉴定到的化合物仍然无法解释相当一部分毒性,特别是在极性分数中,这表明存在未知的极性转化产物和新出现的污染物.

结论:

目前的NTA-EDA方法是有效的识别已知的工业污染物,如POPs和EDCs在共同的矩阵.
像地下水和空气这样的代表性不足的矩阵需要NTA-EDA的更广泛应用.
未确定的极性化合物和转化产品的存在表明,需要开发先进的分析技术来充分了解环境毒性.

关键词:

新出现的污染物引起了人们的关注.以结果为导向的分析.环境污染物环境污染物非有针对性的非有针对性的

更多相关视频

Analysis of Organochlorine Pesticides in a Soil Sample by a Modified QuEChERS Approach Using Ammonium Formate

Analysis of Organochlorine Pesticides in a Soil Sample by a Modified QuEChERS Approach Using Ammonium Formate

Published on: January 20, 2023

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Applying Cheminformatics to Develop a Structure Searchable Database of Analytical Methods

Published on: June 6, 2025

相关概念视频

Types of Toxins

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

Toxic Reactions: Overview

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...