具有固核封闭的相变皮克林乳液,由酸功能化纳米颗粒稳定,以提高β-胡卜素生物可访问性
Like Wang1, Peiyan Feng1, Bo Liu1
1Research and Development Centre of Food Proteins, School of Food Science and Engineering, Guangdong Province Key Laboratory for Green Processing of Natural Products Safety, South China University of Technology, Guangzhou 510640, PR China.
Food chemistry
|October 30, 2025
概括
新型相变皮克林乳液微囊 (PCPEs) 使用修饰的纳米粒子和脂肪酸核心来封装β-胡卜素. 这种固核策略显著改善了β-胡卜素的稳定性和生物可访问性.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
背景情况:
- 囊括像β-胡卜素这样的脂性生物活性物质对于增强稳定性和生物可用性至关重要.
- 传统的乳液系统往往由于分子迁移和不稳定性而遭受降解和低生物可访问性.
- 开发具有改进保护机制的新型输送系统对于功能性食品成分至关重要.
研究的目的:
- 为了构建新的相变皮克林乳液微囊 (PCPEs) 进行有效的β-胡卜素封装.
- 研究酸修饰的纳米颗粒 (T-zein) 在乳液稳定和保护中的作用.
- 评估开发的PCPE中β-胡卜素的稳定性,受控释放和生物可访问性.
主要方法:
- 阶段变换皮克林乳液微囊使用酸修饰的纳米颗粒和酸/牛油酸优性混合物进行合成.
- 纳米颗粒的湿度通过移植酸来调整,以在50°C稳定乳化.
- 评估了封装效率,β-胡卜素在紫外线下降解和氧化,体外消化和生物可访问性.
主要成果:
- 对于β-胡卜素,PCPE实现了88.15%的高封装效率.
- 固化的核心和T-zein外显著减少了β-胡卜素降解57.19% (UV) 和67.88% (氧化).
- 与液核乳液相比,PCPEs表现出增强的胃稳定性,肠道对凝聚的抵抗力,以及36%的β-胡卜素生物可访问性增加.
结论:
- 使用PCPE的固核工程提供了一个强大的平台,用于提供脂友生物活性物质.
- 这种纳米颗粒的酸修饰增强了乳液稳定性和保护性质.
- 开发的PCPE为改善β-胡卜素的稳定性和生物可用性提供了一个有希望的策略.
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