移动健康中的个人内部和个人之间的合规性:在密集的纵向观测研究中对非随机失踪的联合建模方法
Young Won Cho1, Sy-Miin Chow1, Jixin Li2
1Department of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, United States.
JMIR mHealth and uHealth
|October 30, 2025
概括
联合建模有效地解决了移动健康 (mHealth) 和无处不在的健康 (uHealth) 研究中缺少的数据,通过解开人与人之间的因素. 这种方法提高了从密集的纵向数据推断健康行为推断的准确性.
科学领域:
- 医疗信息学 医疗信息学
- 生物统计学 生物统计学
- 行为科学 行为科学
背景情况:
- 缺失的数据在移动健康 (mHealth) 和无处不在的健康 (uHealth) 研究中很常见.
- 非响应受人内部和人间因素的影响,使数据分析复杂化.
- 现有的方法往往无法区分这些因素,特别是在非随机失踪的情况下.
研究的目的:
- 展示用于mHealth/uHealth数据分析的联合建模.
- 展示如何对行为动态和缺失的计算提高了健康行为推断的有效性.
- 在生态瞬间评估和可穿戴设备研究中,说明非可以忽视的缺失的联合建模.
主要方法:
- 应用联合建模对1年的每日基于智能手机的生态瞬间评估 (影响,能量) 和智能手表跟踪的体力活动 (PA) 数据.
- 行为动态的多层面向量自回归模型和失踪的多层面探针模型的组合.
- 与传统的归算方法不同,在模型装配过程中处理了缺失,并进行了灵敏度分析和模拟.
主要成果:
- 联合建模检测到其他方法错过的交叉回归效应;更高的能量预测第二天更高的PA.
- 揭示了不随机缺失 (下PA预测PA缺失) 和随机缺失 (就业状况预测设备-PA缺失) 机制.
- 模拟证实了联合建模,提高了估计准确度,并确定了不可忽视的缺失.
结论:
- 建议在mHealth/uHealth密集型纵向数据中对不可忽视的缺失进行多层分解的联合建模.
- 倡导使用缺失的数据模型来理解机制和指导数据收集.
- 强调为强大的健康行为研究,考虑明显的缺失来源的重要性.
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