短期暴露于臭氧和精神分裂症住院风险:温度调节效应和绿色空间减轻效应
Chuan Li1, Xin Yu1, Rong Song1
1Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China; Center for Big Data and Population Health of IHM, Hefei, Anhui, China; Inflammation and Immune Mediated Diseases Laboratory of Anhui Province, Hefei, Anhui, China.
Environmental pollution (Barking, Essex : 1987)
|October 30, 2025
概括
臭氧污染的增加增加了精神分裂症住院的风险,特别是在高温的情况下. 住宅绿地可以提供对这些环境健康影响的保护.
科学领域:
- 环境健康 环境健康
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 臭氧 (O3) 污染与精神分裂症 (SCZ) 住院之间的联系存在有限的研究.
- 温度和绿色对这种关联的影响需要进一步研究.
研究的目的:
- 检查O3污染和SCZ住院患者之间的关联.
- 评估温度和住宅绿地对这种关系的影响.
主要方法:
- 采用了时间分层的案例交叉研究设计.
- 分析了中国安省 (2017-2020年) 160,551例SCZ住院病例的数据.
- 条件后勤回归和受限制的立方线被用来建模这些关联.
主要成果:
- 暴露于O3与每10μg/m3升高的高温下O3增加3.9%的SCZ住院风险相关 (OR=1.039).
- 这种不良影响在45岁及以上的人群中更为明显.
- 住宅绿地对与O3相关的SCZ住院有显著的缓解作用.
结论:
- 臭氧污染对精神分裂症患者构成风险,特别是在变暖的气候条件下.
- 绿色空间可以作为一种保护因素,减轻空气污染对心理健康的不利影响.
- 公共卫生战略应考虑环境因素和城市绿化,以预防和管理精神分裂症.
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