揭开骨关节炎和代谢特征的共享遗传结构,通过多omics洞察力

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A Pathway Association Study Tool for GWAS Analyses of Metabolic Pathway Information

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Binzhi Liao1, Yumeng Mu1, Mengliang Luo1

  • 1Department of Orthopedic Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Osteoarthritis and cartilage
|October 30, 2025
PubMed
概括

这项研究揭示了骨关节炎 (OA) 和代谢特征 (MTs) 之间的共同遗传因素,确定了关键的基因和途径. 整合代谢数据可以改善骨关节炎的预测,并建议用纤维酸作为潜在的治疗方法.

关键词:
伴随性疾病 伴随性疾病遗传关联是一种遗传关联.代谢过程中的代谢.多个omics的多个omics.骨关节炎是一种骨关节炎.

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