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Updated: Jan 12, 2026

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单次新生儿暴露于普罗波麻醉剂对认知功能的短期和长期影响

Shilei Liu1, Min Feng2, Zhijing Shan1

  • 1Department of Anesthesiology, The Tongliao People's Hospital, China.

The Journal of international medical research
|October 30, 2025
PubMed
概括

新生儿普罗波麻醉对小鼠的神经认知功能没有影响. 研究表明,出生后第12天一次暴露对学习和记忆没有长期影响.

关键词:
普罗波福尔 (Propofol) 是一种大脑衍生的神经营养因子循环腺单酸反应元素结合蛋白质.神经认知功能 神经认知功能后突触密度蛋白-95是什么意思突触性可塑性 突触性可塑性

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相关概念视频

Parenteral Anesthetics: Overview01:24

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Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
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