人类牛奶中B族维生素的参考值:母亲,婴儿和哺乳质量研究 (MILQ)
Lindsay H Allen1, Setareh Shahab-Ferdows2, Sophie E Moore3
1USDA, ARS Western Human Nutrition Research Center, University of California Davis, Davis, CA, United States; Institute for Global Nutrition, Department of Nutrition, University of California, Davis, CA, United States.
Advances in nutrition (Bethesda, Md.)
|October 30, 2025
概括
这项研究确定了人乳中B族维生素的新参考值,发现度低于医学研究所 (IOM) 之前估计的水平. 这些发现影响了婴儿营养建议.
科学领域:
- 人母奶的成分 人母奶的成分
- 营养生物化学 营养生物化学
- 婴儿营养 婴儿营养
背景情况:
- 准确的母乳营养数据对于婴儿健康至关重要.
- 以前的参考值可能不反映当前的营养良好人口.
- 母亲,婴儿和哺乳质量 (MILQ) 研究旨在更新这些值.
研究的目的:
- 确定人乳中B族维生素的参考值 (RV).
- 将MILQ研究结果与医学研究所 (IOM) 建议进行比较.
- 为母乳中B族维生素度提供百分位曲线.
主要方法:
- 在多个国际站点对来自营养良好母亲的母乳样本进行分析.
- 使用了先进的分析技术,包括超高性能液体染色学-质谱学 (UPLC-MS/MS),高性能液体染色学-光检测和竞争性化学发光酶免疫测试.
- 同时分析多种B族维生素 (B2,B3,泛酸,B6,生物素) 和单独分析B1,胆和B12.
主要成果:
- 对B1,B2和B6的MILQ估计值明显低于IOM值 (<60%).
- 对于B3,B12和胆的MILQ估计是IOM值的60%-100%.
- 潘托酸和生物的估计值与IOM值一致或略高 (100%-125%).
- 1-6个月的维生素B摄入量中位数低于B1,B2,B3,B6和B12的IOM充足摄入量 (AI),但高于泛酸和生物素.
结论:
- 人类母乳中维生素B的度,特别是B1,B2和B6的度,低于国际移民组织 (IOM) 以前的假设.
- 根据MILQ数据,当前IOM对几个B族维生素的充足摄入量 (AI) 可能被高估了.
- MILQ参考值为婴儿营养指南和评估提供了关键的更新.
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