设计一个依赖于PLP的Mannichase

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Shaonan Liu1, Yang Hai1

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, Santa Barbara, CA, United States.

Methods in enzymology
|October 30, 2025
PubMed
概括

研究人员将一个依赖于素5'-酸盐 (PLP) 的酶LolT转化为Mannichase. 这种生物催化剂使α,β-氨基酸的高效,选择性合成成为可能,扩大了合成化学的应用.

关键词:
生物催化剂是一种生物催化剂.哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈曼尼赫反应是曼尼赫反应.这是一种依赖PLP的酶.蛋白质工程是一种蛋白质工程.α,β-氨酸是什么?

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