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使用硫胺依赖酶的光生物催化酶的C(sp3) -H乙化

Ronald D Adukure1, Yen-Chu Lu1, Rudi Fasan1

  • 1Department of Chemistry and Biochemistry, The University of Texas at Dallas, Richardson, TX, United States.

Methods in enzymology
|October 30, 2025
PubMed
概括

依赖胺二酸盐 (ThDP) 的酶现在可以进行基因介导的C(sp3) -H键功能化. 这种光生物催化方法使能产生酶选择性子合成,扩大了对不对称合成的酶能力.

关键词:
甲溶解酶的使用方法通过C-H的化.转移原子转移原子的时间激进的NHC化学是什么胺依赖的酶 胺依赖的酶

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