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相关概念视频

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
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Substance Use Disorders Affecting Sleep01:24

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
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Desensitization and Tachyphylaxis01:20

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Tachyphylaxis is described as a rapid decrease in response to a drug after repeated or continuous administration of the same drug dose. It is a phenomenon where the body becomes less responsive to a particular substance or intervention over time, requiring higher doses or stronger interventions to achieve the same effect. It results from adaptive changes in the body's receptors, signaling pathways, or physiological processes that occur in response to prolonged exposure to a stimulus.
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Drug Abuse and Addiction: Pharmacological Phenomena01:15

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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
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Drug Accumulation During Multiple Dosing: Intermittent IV Infusions01:24

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Intermittent intravenous (IV) infusion is a method of drug administration where medications are delivered over short infusion periods followed by intervals of no drug delivery. This approach helps to prevent sustained high drug concentrations in the bloodstream, reducing the risk of adverse effects associated with prolonged exposure. Unlike continuous infusion, steady-state concentrations may not be achieved during a single dosing cycle but can be reached through repeated...
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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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相关实验视频

Updated: Jan 12, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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药物过度使用头痛

Jennifer T Nguyen1, Sunita Dergalust1, Udai Nanda2

  • 1Department of Neurology, West Los Angeles VA Medical Center, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA.

Physical medicine and rehabilitation clinics of North America
|October 30, 2025
PubMed
概括
此摘要是机器生成的。

药物过度使用头痛 (MOH) 是一种普遍存在的二次头痛障碍,影响1%至5%的个人. 它是由于经常过度使用急性头痛治疗在那些有先前存在的初级头痛.

关键词:
药物诱导的头痛是药物引起的药物过度使用头痛多学科的头痛管理反弹性头痛是一种反弹性头痛.二次性头痛二次性头痛戒断的头痛是因为戒断.

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科学领域:

  • 神经学 神经学
  • 头痛 医学 医学 医学

背景情况:

  • 药物过度使用头痛 (MOH) 是一种二次头痛疾病.
  • 它影响到1%至5%的人口.
  • MOH的发展是由于经常过度使用急性头痛治疗方法.

研究的目的:

  • 为了定义药物过度使用头痛 (MOH).
  • 为了确定MOH的风险因素.

主要方法:

  • 关于MOH定义和流行率的文献综述.
  • 分析与MOH发展相关的风险因素.

主要成果:

  • MOH的特点是头痛发生>15天/月.
  • 以前存在的原发性头痛疾病是MOH的主要危险因素.

结论:

  • MOH是一种常见的疾病,与急性药物过量使用有关.
  • 识别和管理先前存在的头痛障碍对于MOH预防至关重要.