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相关概念视频

ER Retrieval Pathway01:45

ER Retrieval Pathway

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In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
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Hepatic Portal System

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The hepatic portal system, a critical part of our circulatory framework, transports nutrient-laden, deoxygenated blood from the gastrointestinal tract and spleen to the liver. This ingenious system plays an indispensable role in maintaining our body's metabolic equilibrium.
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
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Direct Motor Pathways01:11

Direct Motor Pathways

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The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
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Encoding01:19

Encoding

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Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
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Indirect Motor Pathways01:22

Indirect Motor Pathways

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The indirect motor or extrapyramidal pathways originate in the brainstem, the lower portion of the brain that connects it to the spinal cord. They consist of several distinct tracts, each with specialized functions. The four main tracts of the indirect motor pathways are the vestibulospinal tract, the reticulospinal tract, the tectospinal tract, and the rubrospinal tract.
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Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
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相关实验视频

Updated: Jan 12, 2026

Author Spotlight: Investigating the Effects of Mind-Body-Movement Practices on Brain Function
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在ENCODE门户网站上的数据导航.

Meenakshi S Kagda1, Bonita Lam1, Casey Litton1

  • 1Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

Nature communications
|October 31, 2025
PubMed
概括
此摘要是机器生成的。

该ENCODE项目通过广泛的实验和计算分析来确定功能性基因组元素. 最近的更新增强了数据门户,以提高可访问性和用户体验.

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科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 功能性基因组学 功能性基因组学

背景情况:

  • 两个十年来,ENCODE (DNA元素百科全书) 项目一直在确定人类和老鼠基因组中的功能元素.
  • 从23,000多个功能基因组学实验,800多个表征实验和60,000多个计算分析中获得的全面数据是公开可用的.
  • 该项目的最后阶段专注于用于基因组元素表征和验证的新型试验.

研究的目的:

  • 向ENCODE数据门户网站报告最近的更新,改善科学界对数据的可访问性和可用性.
  • 为了突出数据处理,可视化和下载选项的改进.
  • 提供通过统一的处理管道生成的数据的摘要.

主要方法:

  • 开发和维护一个开放访问的数据门户 (https://www.encodeproject.org/).
  • 实施和使用统一的数据处理管道来生成数据.
  • 引入用于基因组元素表征和验证的新型试验.

主要成果:

  • 一个重新设计的ENCODE数据门户主页,以改善用户导航.
  • 增强的搜索界面和为生物相关数据集定制设计的页面.
  • 通过增强的购物车界面,改进了数据可视化和用户友好的下载选项.

结论:

  • 更新后的ENCODE数据门户提供了对综合基因组数据的显著改进.
  • 统一的处理管道确保数据的一致性和可靠性.
  • 这些改进有助于进一步研究人类和小鼠基因组的功能元素.