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Updated: Jan 12, 2026

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通过AEBP2的广泛表达的长异构体对PRC2进行自身抑制

Marlena Mucha1, Zhihao Lai2, Nicholas J McKenzie2

  • 1Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland.

The EMBO journal
|October 31, 2025
PubMed
概括

辅助子单元AEBP2有两个异型,AEBP2L和AEBP2S,它们相反地调节多抑制复合体2 (PRC2) 活动. 在体细胞中,AEBP2L抑制PRC2,而AEBP2S在早期发育过程中促进PRC2.

关键词:
在AEBP2中,AEBP2是AEBP2.化电磁波是一种冷电磁波.在 PRC2 中,PRC2 是 PRC2 的第一个类型.聚合的多元.三重胸部 (trithorax) 是一个三重体.

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