由于职业接触石棉而导致的肺癌的全球负担:1990年至2021年
Qiulin Huang1,2,3, Yongran Cheng4, Ruijiao Lei1,2
1Department of Cancer Prevention, Zhejiang Cancer Hospital, Hangzhou, 310022, China.
Environmental health : a global access science source
|October 31, 2025
概括
25年前实施的全面禁止石棉,显著减少了肺癌发病率,死亡率和DALYs. 这凸显了全球禁止石棉的迫切需要,以减轻职业癌症风险.
科学领域:
- 职业健康 职业健康 职业健康
- 环境流行病学环境流行病学
- 公共卫生政策 公共卫生政策
背景情况:
- 暴露于石棉是肺癌的已知原因之一,但它的使用在全球范围内仍然存在.
- 了解与石棉有关的肺癌的流行病学模式对于公共卫生至关重要.
- 评估禁用石棉对肺癌负担的影响至关重要.
研究的目的:
- 评估因职业接触石棉而造成的全球肺癌负担.
- 分析与石棉有关的肺癌的时间,区域,性别和年龄特定的流行病学模式.
- 评估禁止石棉对肺癌趋势的有效性.
主要方法:
- 从2021年全球疾病负担 (GBD) 中利用的肺癌数据 (发病率,死亡率,DALY)
- 分析了按性别和年龄组的年龄标准化率.
- 雇员Joinpoint回归用于时间趋势分析和全球石棉禁令数据.
主要成果:
- 肺癌发病率,死亡率和DALY大约在石棉禁用后的25年内下降.
- 在2021年,职业石棉暴露导致了全球9.4%的肺癌死亡和7.2%的DALYs.
- 在1990-2021年期间,与石棉有关的肺癌死亡人数增加,负担转移到老年人群.
结论:
- 完全禁止石棉有效地减少了25年后的肺癌发病率,死亡率和DALYs.
- 调查结果强调,迫切需要全面禁止使用石棉,特别是化.
- 政策干预对于减少与石棉相关的肺癌的长期负担至关重要.
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