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Updated: Jan 12, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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绘制非法典拼接变体的地图:解密异常男性不孕症隐藏的遗传结构

Kuokuo Li1,2,3, Yuge Chen1,2,3, Dongdong Tang1,2,3

  • 1Reproductive Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Anhui Medical University, No. 218 Jixi Road, Hefei, Anhui, 230022, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|October 31, 2025
PubMed
概括

非正规拼接变体 (NCSVs) 最近被确定为男性不孕症的重要原因. 这些遗传变异破坏了正常的基因功能,导致了以前无法解释的男性生殖问题的病例.

关键词:
TMF1 TMF1 TMF1 TMF1 TMF1 TMF1 TMF1 TMF1 TMF1男人不孕不育的原因非正典拼接的变种是非正典拼接.

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