慢性鼻炎:内型和临床影响的审查
Tom Raz Yarkoni1, Elchanan Zloczower2, William Jared Martin1
1Department of Otolaryngology - Head & Neck Surgery, University of North Carolina, Chapel Hill, NC, USA.
Ear, nose, & throat journal
|October 31, 2025
概括
了解慢性鼻炎 (CRS) 内型指导精确的诊断和治疗. 区分炎症类型使得包括生物药物在内的向治疗能够改善患者在CRS管理中的结果.
科学领域:
- 免疫学 免疫学 免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏 过敏是一种过敏.
背景情况:
- 慢性鼻炎 (CRS) 是一种复杂的上呼吸道炎症疾病.
- 目前的理解超越了简单的表型,转向了分子和免疫学内型.
- 内型化CRS对于有效管理至关重要.
研究的目的:
- 审查有关慢性鼻炎 (CRS) 末型的当前文献.
- 评估CRS内型的临床影响.
- 突出表现内型特异性治疗的影响.
主要方法:
- 关于CRS内型的当前研究的文献综述.
- 基于内型分类的诊断和治疗方法的分析.
- 评估分子和免疫学标记物的作用.
主要成果:
- 了解CRS内型已经改变了诊断和治疗策略.
- 将炎症分为2型和非2型可以进行向治疗.
- 生物药物代表了内型特异性治疗的重大进步.
结论:
- 未来的研究将集中在个性化医疗的生物标志物识别上.
- 个性化,内型特异性疗法是改善CRS结果的关键.
- 精准医学的进步有望进一步完善CRS管理.
相关概念视频
Chronic Pharyngitis
10.8K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
10.8K
Anatomy of Respiratory System I: Upper Respiratory Tract
4.7K
The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
Nose and nasal cavity
The nose and nasal cavity represent the main external openings of the respiratory tract....
4.7K
Physical Assessment of the Respiratory Tract I: Health History
822
Physical assessment of the respiratory tract is critical to patient care. It allows healthcare professionals to identify and manage various respiratory conditions. The process involves a combination of subjective and objective data collection.
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
822
COPD: Pathogenesis and Clinical Features
1.7K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
1.7K
Tonsillitis I: Introduction
1.7K
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat.
Etiology
Three primary contributing factors have been identified.
Etiology
Three primary contributing factors have been identified.
1.7K
Common Respiratory Disorders
1.3K
Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.3K


