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Updated: Jan 12, 2026

In-vitro Reconstitution of Bacterial Ubiquitination and VCP/p97-mediated Elimination
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在调节免疫细胞功能的过程中,ubiquitin结合酶的作用

Saci-Elodie Marty1, Linda Yip1, Fangyuan Wang1

  • 1Department of Medicine, School of Medicine, Stanford University, Palo Alto, CA, United States.

Frontiers in immunology
|October 31, 2025
PubMed
概括

调节性T细胞 (Tregs) 中IL-2受体信号的破坏会损害免疫耐受性,导致自身免疫性疾病. 通过抑制化来恢复这种信号传递,为自身免疫提供了治疗潜力.

关键词:
格莱尔的葡萄杯是什么意思作为IL-2受体的信号传递器.库林环结合酶 (CRLs) 是一种没有脱,没有脱.尼迪化激活酶抑制剂 (NAEi) 的使用.在pJAK1降解过程中,监管性T细胞 (Treg) 的使用

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