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Updated: Jun 29, 2026

Visualizing Non-lytic Exocytosis of Cryptococcus neoformans from Macrophages Using Digital Light Microscopy
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在Cryptococcus neoformans中,B1脂酶对于老鼠大脑中的加密球菌形成至关重要

Melissa E Munzen1, Glauber R de Sousa Araújo2, Mohamed F Hamed1,3

  • 1Department of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, United States.

Frontiers in immunology
|October 31, 2025
PubMed
概括

脂酶B1 (PLB1) 对于Cryptococcus neoformans (Cn) 脑部感染至关重要. 禁用PLB1降低了真菌生存率,囊多糖分的扩散和生物膜的形成,突出显示PLB1是潜在的抗真菌标.

关键词:
这是Cryptococcus neoformans的新型菌.粘附性 粘附性 粘附性 粘附性囊囊是一个囊.大脑的加密菌病.这就是Cryptococcoma.菌生物膜是一种真菌生物膜.脂酶是一种脂酶.聚糖是一种多糖.

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Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...