在艾滋病毒感染者中使用心血管疾病预防措施
Nadine Jaschinski1, Bastian Neesgaard1, Ferdinand Wit2
1CHIP, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Open forum infectious diseases
|October 31, 2025
概括
患有高心血管疾病 (CVD) 风险的艾滋病毒感染者比例增加,但服用抗高血压药物和降脂药物等预防措施的比例没有显著增加. 对于这一群体来说,需要提高对心血管疾病风险管理的认识.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 关于艾滋病毒感染者采取心血管疾病 (CVD) 预防措施的数据有限.
- 心血管疾病对艾滋病毒感染者构成重大风险.
研究的目的:
- 为了确定心血管疾病的年度流行率,在艾滋病毒感染者中使用预防措施,估计10年心血管疾病风险非常高.
- 评估与采取特定预防措施相关的因素.
主要方法:
- 该研究分析了RESPOND队列参与者的2012-2021年的数据.
- 双项回归被用来评估影响采用心脏病预防措施的因素.
- 每项措施的资格是基于D:A:D10年心血管疾病风险超过10%的标准.
主要成果:
- 在2012年至2021年期间,高风险个体的比例从32.4%增加到52.1%.
- 抗高血压药 (67.4%),降脂药 (55.9%) 和戒烟 (7.4%) 的摄入率没有显著的时间变化.
- 抗糖尿病药物的使用略有下降,而ACEI/ARB的使用在增加之前出现了小幅下降;病毒病和药物使用与吸收率较低有关.
结论:
- 艾滋病毒感染者中高心血管疾病风险的患病率不断上升,但预防措施的使用量没有相应增加,这凸显了护理方面的关键差距.
- 提高对心血管疾病风险管理策略的认识和实施对于常规临床环境中的艾滋病毒感染者至关重要.
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