血管运动性鼻炎:当前的概念和新兴的治疗方法
Ghezlan Aldawas1,2, Imtiyaz N Bhat1
1Otolaryngology, Head and Neck Surgery, Farwaniya Hospital, Kuwait City, KWT.
Cureus
|October 31, 2025
概括
血管运动性鼻炎 (VMR) 是一种常见的非过敏性鼻腔疾病,常常被误诊. 有效的管理涉及触发器避免和鼻内治疗,神经特异性疗法在耐火病例中显示出希望.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 神经科学是一个神经科学.
背景情况:
- 血管运动性鼻炎 (VMR) 是一种普遍存在的非传染性,非过敏性鼻炎亚型.
- 像鼻塞和鼻这样的VMR症状模仿过敏性鼻炎,导致误诊和治疗不足.
研究的目的:
- 审查血管运动性鼻炎的病理生理学和当前治疗策略.
- 突出VMR的诊断挑战和管理方法.
主要方法:
- 在PubMed,EMBASE和Cochrane图书馆 (2000-2025) 的系统文献搜索.
- 包括随机对照试验,队列研究和临床指南.
- 不包括案例报告和非英语研究.
主要成果:
- VMR病理生理学涉及自主神经系统失调,神经可塑性,炎症和TRP通道过度刺激.
- 鼻腔内用易普拉胺对鼻有效;其他治疗方法包括皮质类固醇和抗组胺药物.
- 对于耐火VMR,正在研究神经切除等手术选择.
结论:
- VMR需要逐步的,基于触发的管理.
- 传统的鼻内治疗是第一线治疗,而神经特异性治疗可能会导致复发症状.
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