基于应用程序的多模式生活方式干预基本高血压 (HYPE):一个分散的随机对照试验
Christian Beger1, Marco Lehmann2, Marisa Kaup2
1Vascular Medicine Research, Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Germany.
Frontiers in digital health
|October 31, 2025
概括
基于应用程序的生活方式干预显著降低了非控制高血压的成年人的血压. 这种数字化方法改善了体重,生活质量和食物素养,为高血压管理提供了有前途的工具.
科学领域:
- 心血管医学 心血管医学
- 数字健康数字健康
- 公共卫生 公共卫生
背景情况:
- 生活方式干预对于管理高血压和心血管风险至关重要.
- 生活方式干预措施的不良实施阻碍了它们的有效性.
- 基于应用程序的干预措施提供了一个可扩展的解决方案,以改善坚持和结果.
研究的目的:
- 评估基于应用程序的多式生活方式干预措施降低无控制高血压患者血压 (BP) 的有效性.
- 评估干预措施对二次结果的影响,包括透析血压,体重,生活质量和食物素养.
主要方法:
- 一个分散的,单盲,随机对照试验,涉及139名患有失控高血压的成年人.
- 参与者被随机分配到为期12周的基于应用程序的生活方式干预或常规护理.
- 通过链式方程 (MICE) 进行了多重归算的治疗意图分析.
主要成果:
- 干预组在12周后经历了缩血压 (-8.5 mmHg) 和腹缩血压 (-5.06 mmHg) 的显著降低.
- 干预组的体重,与健康有关的生活质量和食物素养有显著的改善.
- 该干预措施在所有测量结果中显示出一致且大的影响,没有严重的不良事件.
结论:
- 数字多式生活方式干预可以在临床上改善高血压护理.
- 这些发现支持使用基于应用程序的干预措施来改善高血压患者的血压控制和整体健康状况.
- 需要进行更大规模的试验,以进一步验证这些有希望的结果在不同人群中.
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