在儿科患者中探索长期COVID:来自长期COVID诊所的临床见解
Dina Kamel1,2, My H Vu3, Jeffery Bender1,2
1Division of Infectious Diseases, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, United States.
Frontiers in pediatrics
|October 31, 2025
概括
长期COVID在儿童中表现为持续的疲劳和头痛. 症状出现后接种疫苗可能会改善一些儿科患者的症状,但需要更多的研究.
科学领域:
- 儿童传染病 儿童传染病
- 青少年健康 青少年健康
- 纵向健康研究 纵向健康研究
背景情况:
- 长期COVID,定义为SARS-CoV-2感染后的持续症状,影响儿童和青少年.
- 对于儿科症状模式和疫苗接种对长期COVID的影响的了解有限.
- 这项研究解决了儿科长期COVID轨迹的知识差距.
研究的目的:
- 为了描述儿科长期COVID的症状模式.
- 研究疫苗接种对儿童和青少年疾病进展的影响.
- 评估疫苗在缓解长期COVID症状方面的有效性.
主要方法:
- 在专门的长期COVID诊所对123名0-21岁的患者进行了回顾性研究.
- 纳入标准:在SARS-CoV-2感染后4周以上持续或出现新症状.
- 收集关于症状持续时间,患病率和疫苗接种状态的数据.
主要成果:
- 在不同年龄组中,最常见的症状是疲劳 (93%) 和头痛 (70%).
- 女性患者报告脑雾,头,心跳和POTS的比率更高.
- 虽然基线疫苗接种没有改变最初的症状持续时间,但41%的接种后COVID疫苗的人报告了改善.
结论:
- 儿科长期COVID涉及长期的多系统症状.
- 接种疫苗可以为一些儿科患者提供主观的症状缓解.
- 进一步的前性研究对于澄清疫苗在儿科长期COVID管理中的作用至关重要.
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