在持久性心房动中对心律失常原基质的高密度评估
Haseeb Valli1, Mahmoud Ehnesh2, Sam Coveney3
1Heart Rhythm Centre, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, Hill End Road, Harefield, Uxbridge, United Kingdom.
Heart rhythm O2
|October 31, 2025
概括
全极技术 (OT) 和双极电压 (BiV) 地图显示,心房节律显著影响左心房 (LA) 的低电压区域 (LVAs). 门调整是必要的,以使OT能够准确地识别心房动 (AF) 中的节律失常基质.
科学领域:
- 电子生理学 电子生理学
- 进行心脏映射.
- 前庭的研究研究.
背景情况:
- 左心房 (LA) 纤维化是心房动 (AF) 失常的关键因素.
- 在LA的低压区域 (LVAs) 被认为是纤维化指标和切除的潜在目标.
- 目前用于识别LA LVAs的标准,特别是在万极技术 (OT) 映射方面,尚未得到充分确立.
研究的目的:
- 评估OT和常规双极电压 (BiV) 映射在AF和规律节律的患者之间的相关性.
- 确定不同的映射技术和心房节律如何影响LA电压和LVAs的表征.
主要方法:
- 双极性和OT电压映射在17名患者中进行,这些患者因持续性AF而接受了de novo切除.
- 在AF和冠状动脉鼻节奏 (CSP) 期间,在600毫秒内进行了映射.
- 低电压被定义为BiV < 0.5 mV.
主要成果:
- 在AF期间的LA电压对BiV (r=0.15) 和OT (r=0.16) 显示与CSP的相关性较差.
- 在AF和CSP期间,OT始终比BiV产生更高的电压测量 (p < .050).
- 根据心房节律和映射方法,LVA负担有显著的变化 (AF-BiV: 65.0%,AF-OT: 56.2%,CSP-BiV: 34.2%,CSP-OT: 24.56%;p < .050).
结论:
- 映射技术 (OT vs. BiV) 和心房节律 (AF vs. CSP) 都显著影响LA电压和LVA量化.
- 单一的,用于识别LVAs的通用电压值不适合双极和OT在不同节奏的映射.
- OT测量高于BiV,因此需要调整值,以便在AF切除中准确地表征基质.
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