在辐射诱导的口腔粘膜炎中,抗氧化剂的全身或局部管理
Saikiran Bahadur1, Diksha Koushal2, Eesha3
1Departments of Prosthodontics, Springfield Dental, Springfield, Massachussets, United State of America.
Bioinformation
|October 31, 2025
概括
这项研究比较了头癌患者的辐射诱导口腔粘膜炎的全身和局部抗氧化剂疗法. 局部抗氧化剂,特别是黄凝,在控制这种衰弱的副作用方面表现出卓越的有效性.
科学领域:
- 在瘤学瘤学.
- 辐射疗法 辐射疗法
- 口腔医学是指口腔医学.
背景情况:
- 口腔粘膜炎 (OM) 是头癌的放射治疗后的一种严重并发症.
- 它显著影响患者的生活质量和治疗坚持.
研究的目的:
- 为了比较系统与局部抗氧化剂治疗的有效性,以预防和管理辐射诱导的OM.
- 在这些输送方法中评估特定的抗氧化剂.
主要方法:
- 一项随机研究涉及150名接受放射治疗的头癌患者.
- 患者被分配到系统或局部抗氧化剂组,并进一步按药剂进行细分.
- 使用世界卫生组织 (WHO) 口腔粘膜炎量表来评估口腔粘膜炎的严重程度.
主要成果:
- 系统和局部抗氧化剂疗法都有效地减少了口腔粘膜炎的严重程度.
- 局部抗氧化剂应用,特别是黄凝,与系统方法相比,表现出更大的疗效.
结论:
- 抗氧化剂治疗是治疗辐射诱导的口腔粘膜炎的可行策略.
- 局部应用,特别是黄凝,在接受放射治疗的头癌患者中为OM提供了更有效的治疗选择.
更多相关视频
07:44Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
11.9K
06:39Author Spotlight: Exploring Photodynamic Therapy with Curcumin in a Murine Model for Oral Candidiasis
Published on: October 27, 2023
1.4K
相关概念视频
01:24Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
1.4K
In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
1.4K
02:49Cancer Therapies
9.8K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
9.8K