血清丸激素水平与40-65岁巴基斯坦男性勃起功能障碍严重程度之间的相关性

Khalil Ur Rehman¹, Fazle Manan¹, Mir Abid Jan²

¹Department of Urology, Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar, Peshawar, PAK.

Cureus

|October 31, 2025

概括

低水平与巴基斯坦男性的勃起功能障碍 (ED) 严重程度密切相关. 这项研究强调了测量ED男性血清丸激素的重要性,以指导治疗.

科学领域:

安德罗学与人类学
泌尿器科泌尿器科泌尿器科泌尿器科
内分泌学在内分泌学.

背景情况:

勃起功能障碍 (ED) 是一个普遍的全球健康问题,有多因素的原因,包括荷尔蒙失衡.
缺乏症是ED的公认贡献者,需要研究其与ED严重程度的关联.

研究的目的:

调查40-65岁的巴基斯坦男性血清总水平和ED严重程度之间的相关性.
评估丸激素测量的诊断实用性,以评估这个人口中的ED.

主要方法:

一项涉及110名巴基斯坦男性 (40-65岁) 患有ED的横截面研究.
使用国际勃起功能指数-5 (IIEF-5) 量化ED严重程度.
血清总丸激素通过化学发光免疫测试测量;斯皮尔曼的等级相关性分析了与IIEF-5分数的关系.

主要成果:

在血清总和IIEF-5分数之间观察到显著的正相关性 (斯皮尔曼的p = 0.615,p < 0.0001).
与轻度ED (432.8 ng/dL) 相比,患有严重ED的男性表现出显著较低的水平 (278.6 ng/dL).
随着ED严重程度的增加,水平逐渐下降 (p < 0.0001).

结论:

血清总水平显示出与巴基斯坦男性ED严重程度的强烈,显著的积极关联.
这些发现支持在ED治疗中进行常规的荷尔蒙评估,特别是测量丸激素,特别是在怀疑患有阴性双胞胎症的情况下.

关键词:

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