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在质谱学指导下发现了新型GCPII抑制剂支架

Robyn Wiseman1,2, Ajit G Thomas1, John Janiszewski3

  • 1Johns Hopkins Drug Discovery, Johns Hopkins School of Medicine, Baltimore, MD, United States.

Frontiers in pharmacology
|October 31, 2025
PubMed
概括

通过使用一种新的查试验,确定了新型的谷氨酸糖酶II (GCPII) 抑制剂. 这些化合物通过改善GCPII抑制的脑透来治疗神经系统疾病的潜力.

关键词:
酵素酶是一种酶.谷氨酸甲基碳氧二酶II (GCPII) 的使用抑制剂抑制剂的使用质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量查检查 查检查 查检查 查检查

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