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在以太取代的NIR捐赠者-接受者-捐赠者光体的位置调节

Maryam Ghazala¹, Santana P Garcia¹, Cameron F L Sheldon¹

¹Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio 43210, United States.

The journal of physical chemistry. A

|October 31, 2025

概括

捐赠组在近红外 (NIR) 光体中的位置显著影响其光学特性和稳定性. 超定位的捐赠者提高了量子产量,而对定位的捐赠者则扩展了生物成像应用的发射波长.

科学领域:

有机化学有机化学
光物理学的光学物理学
材料科学材料科学材料科学

背景情况:

近红外 (NIR) 供体-接受体-供体 (D-A-D) 光体对于生物成像至关重要.
分子架构的修改可以提高溶解度,减少光火.
替代物位置对D-A-D光体光物理学的影响仍未得到充分研究.

研究的目的:

综合分析捐赠体替代物的位置如何影响D-A-D NIR光体的稳定性和光学特性.
为了研究一系列D-A-D NIR光体的结构-性质关系,具有不同的 methoxy 供体位置.

主要方法:

通过与六种不同的 methoxyphenyl 或 dimethoxyphenyl 供体结合 thienothiadiazole (TTD) 来合成 D-A-D NIR 光体库.
光物理性质的实验性表征,包括辐射波长和量子产量.
密度函数理论 (DFT) 计算以支持实验发现.

主要成果:

甲基替代剂的位置与辐射波长,亮度和稳定性有很强的相关性.
相对位置的捐赠者导致更长的发射波长 (907 nm) 与meta-positioned捐赠者 (888 nm) 相比.
超定位的供体表现出更高的量子产量 (0.88-0.90%) 比正位和对位的对应物 (0.31-0.47%).
由于硬体应变,二-奥托替代显著降低了光稳定性.

结论:

供体替代物位置是调整D-A-D NIR光子性能的一个关键因素.
假定位置的捐赠器适用于需要更长的发射波长的应用.
在生物成像中要求高量子产量的应用中,meta定位的捐赠者是有希望的.

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